Gene

babam2

ID
ZDB-GENE-050417-299
Name
BRISC and BRCA1 A complex member 2
Symbol
babam2 Nomenclature History
Previous Names
  • bre
  • im:7141046
  • zgc:110368 (1)
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Predicted to enable polyubiquitin modification-dependent protein binding activity. Predicted to be involved in several processes, including mitotic G2 DNA damage checkpoint signaling; positive regulation of DNA repair; and response to ionizing radiation. Predicted to act upstream of or within DNA repair. Predicted to be located in cytoplasm and nucleus. Predicted to be part of BRCA1-A complex and BRISC complex. Orthologous to human BABAM2 (BRISC and BRCA1 A complex member 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
la020140TgTransgenic insertionUnknownUnknownDNA
sa14574Allele with one point mutationUnknownPremature StopENU
sa23156Allele with one point mutationUnknownPremature StopENU
sa28910Allele with one point mutationUnknownSplice SiteENU
sa36490Allele with one point mutationUnknownPremature StopENU
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Sequence Targeting Reagents
No data available
Human Disease
Associated With babam2 Human Ortholog
No data available
Associated With babam2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR010358 BRCA1-A complex subunit BRE
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Domain Details Per Protein
Protein Additional Resources Length BRCA1-A complex subunit BRE
UniProtKB:Q568D5 InterPro 386
UniProtKB:A0A8M9P8W4 InterPro 386
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 17
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA babam2-201 (1) Ensembl 4,220 nt
mRNA babam2-202 (1) Ensembl 1,215 nt
mRNA babam2-203 (1) Ensembl 266 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH73-221A5ZFIN Curated Data
Contained inBACDKEY-16J16ZFIN Curated Data
Contained inBACDKEY-61N11ZFIN Curated Data
EncodesESTIMAGE:7141046Thisse et al., 2004
EncodescDNAMGC:110368ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanBABAM22
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
MouseBabam25
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
Citations
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