Gene
cldn19
- ID
- ZDB-GENE-050417-242
- Name
- claudin 19
- Symbol
- cldn19 Nomenclature History
- Previous Names
-
- zgc:112141
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable structural molecule activity. Predicted to be involved in bicellular tight junction assembly and cell adhesion. Predicted to be located in cell junction and membrane. Predicted to be active in bicellular tight junction and plasma membrane. Is expressed in brain. Human ortholog(s) of this gene implicated in renal hypomagnesemia 5 with ocular involvement. Orthologous to human CLDN19 (claudin 19).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Baltzegar et al., 2013
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| renal hypomagnesemia 5 with ocular involvement | Alliance | Hypomagnesemia 5, renal, with ocular involvement | 248190 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Claudin | Claudin, conserved site | PMP-22/EMP/MP20/Claudin |
|---|---|---|---|---|
|
UniProtKB:A0A8M6Z120
|
218 | |||
|
UniProtKB:A0A8M6Z925
|
222 | |||
|
UniProtKB:Q567D5
|
209 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cldn19-201
(1)
|
Ensembl | 1,457 nt |
Interactions and Pathways
No data available
Plasmids
No data available