Gene

f3b

ID
ZDB-GENE-050417-234
Name
coagulation factor IIIb
Symbol
f3b Nomenclature History
Previous Names
  • TFb (1)
  • zgc:112151
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have cytokine receptor activity. Involved in vasculature development. Predicted to localize to integral component of membrane and plasma membrane. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma; disseminated intravascular coagulation; and von Willebrand's disease. Is expressed in hindbrain and otic vesicle. Orthologous to human F3 (coagulation factor III, tissue factor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Zhou et al., 2011
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With f3b Human Ortholog
No data available
Associated With f3b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003961 Fibronectin type III
Domain IPR015373 Interferon/interleukin receptor domain
Family IPR001187 Tissue factor
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR036116 Fibronectin type III superfamily
Domain Details Per Protein
Protein Length Fibronectin type III Fibronectin type III superfamily Immunoglobulin-like fold Interferon/interleukin receptor domain Tissue factor
UniProtKB:B0UY88 288
UniProtKB:Q567C9 199
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations