ZFIN is now using GRCz12tu for Genomic Data
Gene
cart2
- ID
- ZDB-GENE-050417-23
- Name
- cocaine- and amphetamine-regulated transcript 2
- Symbol
- cart2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable neuropeptide hormone activity. Predicted to be involved in positive regulation of cell communication and signal transduction. Predicted to act upstream of or within several processes, including adult feeding behavior; negative regulation of appetite; and positive regulation of MAPK cascade. Predicted to be located in extracellular space. Is expressed in basal plate midbrain region; brain; gut; and neurons. Human ortholog(s) of this gene implicated in alcohol dependence; alcohol use disorder; and obesity. Orthologous to human CARTPT (CART prepropeptide).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 16 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:110124 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | CART, C-terminal domain superfamily | CART satiety factor |
|---|---|---|---|---|
| UniProtKB:Q568S2 | InterPro | 120 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers