Gene

srd5a2b

ID
ZDB-GENE-050417-182
Name
steroid-5-alpha-reductase, alpha polypeptide 2b
Symbol
srd5a2b Nomenclature History
Previous Names
  • zgc:112455
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have 3-oxo-5-alpha-steroid 4-dehydrogenase activity. Predicted to be involved in steroid biosynthetic process. Predicted to localize to integral component of membrane and organelle membrane. Is expressed in hindbrain; pectoral fin; and testis. Human ortholog(s) of this gene implicated in hypospadias and prostate cancer. Orthologous to human SRD5A2 (steroid 5 alpha-reductase 2).
Genome Resources
Note
None
Expression
All Expression Data
8 figures from 3 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With srd5a2b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Pseudovaginal perineoscrotal hypospadias 264600
Associated With srd5a2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001104 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal
Family IPR016636 3-oxo-5-alpha-steroid 4-dehydrogenase
Family IPR039357 3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase
Domain Details Per Protein
Protein Length 3-oxo-5-alpha-steroid 4-dehydrogenase 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal 3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase
UniProtKB:Q566V2 217
UniProtKB:F8W397 231
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations