Gene
arfip2b
- ID
- ZDB-GENE-050417-131
- Name
- ADP-ribosylation factor interacting protein 2b
- Symbol
- arfip2b Nomenclature History
- Previous Names
-
- im:7136059
- zgc:112066
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable phospholipid binding activity. Predicted to be involved in intracellular protein transport and regulation of Arp2/3 complex-mediated actin nucleation. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Predicted to be active in trans-Golgi network membrane. Is expressed in several structures, including anterior axial hypoblast; digestive system; hatching gland; mesoderm; and pronephric duct. Orthologous to human ARFIP2 (ARF interacting protein 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:112066 (11 images)
- IMAGE:7136059 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | AH/BAR domain superfamily | Arfaptin family | Arfaptin homology (AH) domain |
|---|---|---|---|---|---|
| UniProtKB:A0A8M3BCZ0 | InterPro | 384 | |||
| UniProtKB:A0A8M9Q652 | InterPro | 344 | |||
| UniProtKB:A0A8M2B217 | InterPro | 395 | |||
| UniProtKB:A0A8M3B667 | InterPro | 365 | |||
| UniProtKB:A0A8M3AWP5 | InterPro | 376 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
arfip2b-201
(1)
|
Ensembl | 1,749 nt | ||
| mRNA |
arfip2b-202
(1)
|
Ensembl | 639 nt | ||
| mRNA |
arfip2b-203
(1)
|
Ensembl | 1,096 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-22L17 | ZFIN Curated Data | |
| Encodes | EST | IMAGE:7136059 | Thisse et al., 2004 | |
| Encodes | cDNA | MGC:112066 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:191571 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001017649 (1) | 1629 nt | ||
| Genomic | GenBank:BX530069 (2) | 222308 nt | ||
| Polypeptide | UniProtKB:A0A8M2B217 (1) | 395 aa |
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Braasch, I., Gehrke, A.R., Smith, J.J., Kawasaki, K., Manousaki, T., Pasquier, J., Amores, A., Desvignes, T., Batzel, P., Catchen, J., Berlin, A.M., Campbell, M.S., Barrell, D., Martin, K.J., Mulley, J.F., Ravi, V., Lee, A.P., Nakamura, T., Chalopin, D., Fan, S., Wcisel, D., Cañestro, C., Sydes, J., Beaudry, F.E., Sun, Y., Hertel, J., Beam, M.J., Fasold, M., Ishiyama, M., Johnson, J., Kehr, S., Lara, M., Letaw, J.H., Litman, G.W., Litman, R.T., Mikami, M., Ota, T., Saha, N.R., Williams, L., Stadler, P.F., Wang, H., Taylor, J.S., Fontenot, Q., Ferrara, A., Searle, S.M., Aken, B., Yandell, M., Schneider, I., Yoder, J.A., Volff, J.N., Meyer, A., Amemiya, C.T., Venkatesh, B., Holland, P.W., Guiguen, Y., Bobe, J., Shubin, N.H., Di Palma, F., Alföldi, J., Lindblad-Toh, K., Postlethwait, J.H. (2016) The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons. Nature Genetics. 48(4):427-37
- Sobral, D., Tassy, O., and Lemaire, P. (2009) Highly Divergent Gene Expression Programs Can Lead to Similar Chordate Larval Body Plans. Current biology : CB. 19(23):2014-2019
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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