Gene
mocos
- ID
- ZDB-GENE-050327-94
- Name
- molybdenum cofactor sulfurase
- Symbol
- mocos Nomenclature History
- Previous Names
-
- im:7142948
- zgc:110784 (1)
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to enable Mo-molybdopterin cofactor sulfurase activity. Predicted to be involved in molybdopterin cofactor metabolic process. Is expressed in neural crest. Human ortholog(s) of this gene implicated in xanthinuria. Orthologous to human MOCOS (molybdenum cofactor sulfurase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7142948 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| xanthinuria type II | Alliance | Xanthinuria, type II | 603592 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000192 | Aminotransferase class V domain |
| Domain | IPR005302 | Molybdenum cofactor sulfurase, C-terminal |
| Domain | IPR005303 | Molybdenum cofactor sulfurase, middle domain |
| Family | IPR028886 | Molybdenum cofactor sulfurase |
| Homologous_superfamily | IPR011037 | Pyruvate kinase-like, insert domain superfamily |
| Homologous_superfamily | IPR015421 | Pyridoxal phosphate-dependent transferase, major domain |
| Homologous_superfamily | IPR015422 | Pyridoxal phosphate-dependent transferase, small domain |
| Homologous_superfamily | IPR015424 | Pyridoxal phosphate-dependent transferase |
Domain Details Per Protein
| Protein | Length | Aminotransferase class V domain | Molybdenum cofactor sulfurase | Molybdenum cofactor sulfurase, C-terminal | Molybdenum cofactor sulfurase, middle domain | Pyridoxal phosphate-dependent transferase | Pyridoxal phosphate-dependent transferase, major domain | Pyridoxal phosphate-dependent transferase, small domain | Pyruvate kinase-like, insert domain superfamily |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M1N4Y2
|
851 | ||||||||
|
UniProtKB:A0A8M3B7X2
|
720 | ||||||||
|
UniProtKB:A2VD33
|
831 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available