Gene

smpdl3a

ID

ZDB-GENE-050327-61

Name

sphingomyelin phosphodiesterase acid like 3A

Symbol

smpdl3a Nomenclature History

Previous Names

si:ch211-199i15.3
zgc:113352

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Predicted to enable metal ion binding activity and sphingomyelin phosphodiesterase activity. Predicted to act upstream of or within sphingomyelin catabolic process. Predicted to be located in extracellular space. Orthologous to human SMPDL3A (sphingomyelin phosphodiesterase acid like 3A).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With smpdl3a Human Ortholog

No data available

Associated With smpdl3a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR004843	Calcineurin-like phosphoesterase domain, ApaH type
Domain	IPR041805	Acid sphingomyelinase/endopolyphosphatase, metallophosphatase domain
Domain	IPR045473	Sphingomyelin phosphodiesterase, C-terminal domain
Family	IPR017064	Acid sphingomyelinase-like phosphodiesterase, predicted
Homologous_superfamily	IPR029052	Metallo-dependent phosphatase-like