Gene

ippk

ID

ZDB-GENE-050327-41

Name

inositol 1,3,4,5,6-pentakisphosphate 2-kinase

Symbol

ippk Nomenclature History

Previous Names

ipk1 (1)
ipk1l (1)
si:dkey-42i9.3
zgc:110769

Type

protein_coding_gene

Location

Chr: 22 Mapping Details/Browsers

Description

Exhibits inositol pentakisphosphate 2-kinase activity. Involved in epithelial cilium movement involved in determination of left/right asymmetry and melanosome transport. Localizes to centrosome and ciliary basal body. Is expressed in axial mesoderm; blastodisc; germ ring; margin; and tail bud. Orthologous to human IPPK (inositol-pentakisphosphate 2-kinase).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

IMAGE:6894363 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 5 figures from 3 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ippk Human Ortholog

No data available

Associated With ippk Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR009286	Inositol-pentakisphosphate 2-kinase
Homologous_superfamily	IPR043001	Inositol-pentakisphosphate 2-kinase, N-terminal lobe

Domain Details Per Protein

Protein	Length	Inositol-pentakisphosphate 2-kinase	Inositol-pentakisphosphate 2-kinase, N-terminal lobe
UniProtKB:B2GT43 InterPro	483
UniProtKB:Q4JL91 InterPro	483

Transcripts

Genome Browsers

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	ippk-201 (1) Ensembl	Ensembl		2,412 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations