Gene
acp1
- ID
- ZDB-GENE-050327-12
- Name
- acid phosphatase 1
- Symbol
- acp1 Nomenclature History
- Previous Names
-
- im:6910498
- zgc:110844
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to have protein tyrosine phosphatase activity. Involved in pronephros development. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including attention deficit hyperactivity disorder; conduct disorder; diabetes mellitus (multiple); diabetic retinopathy; and obesity. Is expressed in gut and liver. Orthologous to human ACP1 (acid phosphatase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6910498 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Li et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR023485 | Phosphotyrosine protein phosphatase I |
| Family | IPR002115 | Protein-tyrosine phosphatase, low molecular weight, mammalian |
| Family | IPR017867 | Protein-tyrosine phosphatase, low molecular weight |
| Family | IPR050438 | Low Molecular Weight Phosphotyrosine Protein Phosphatase |
| Homologous_superfamily | IPR036196 | Phosphotyrosine protein phosphatase I superfamily |
Domain Details Per Protein
| Protein | Length | Low Molecular Weight Phosphotyrosine Protein Phosphatase | Phosphotyrosine protein phosphatase I | Phosphotyrosine protein phosphatase I superfamily | Protein-tyrosine phosphatase, low molecular weight | Protein-tyrosine phosphatase, low molecular weight, mammalian |
|---|---|---|---|---|---|---|
|
UniProtKB:F1QH99
|
158 | |||||
|
UniProtKB:A0A8M1P258
|
158 |
Interactions and Pathways
No data available
Plasmids
No data available