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ZIRC
ZFIN ID: ZDB-GENE-050320-135
Gene Name: mitoguardin 2
Gene Symbol: miga2    Nomenclature History

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Previous Names: fam73b (1), zgc:113131

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Predicted to have protein heterodimerization activity and protein homodimerization activity. Predicted to be involved in mitochondrial fusion. Predicted to localize to the integral component of plasma membrane. Orthologous to human MIGA2 (mitoguardin 2).
Genome Resources: Alliance (1),  Gene:541431 (1),  Ensembl(GRCz11):ENSDARG00000089357 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:113131]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa12133 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa29498 Point Mutation Unknown Premature Stop ENU
    sa37215 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH miga2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH miga2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process mitochondrial fusion (more)
    Cellular Component integral component of plasma membrane (more)
    Molecular Function protein heterodimerization activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR019392 (1)
  • Pfam:PF10265 (1)
  • TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM miga2 No data available
    MARKER RELATIONSHIPS
    miga2 Encodes: [cDNA] MGC:113131 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001013557 (1) 2265 bp
    Genomic GenBank:FO704859 (1) 34233 bp
    Select Tool
    Polypeptide UniProtKB:F1QJS1 (1) 596 aa
    Sequence Clusters UniGene:38403 (1)
    Sequence Information (all 16)
    ORTHOLOGY for miga2 ( Chr: 21 )
    CITATIONS (20)