ZFIN is now using GRCz12tu for Genomic Data
Gene
ptpn18
- ID
- ZDB-GENE-050320-12
- Name
- protein tyrosine phosphatase non-receptor type 18
- Symbol
- ptpn18 Nomenclature History
- Previous Names
-
- zgc:113105
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable protein tyrosine phosphatase activity. Predicted to be active in cytoplasm and nucleus. Orthologous to human PTPN18 (protein tyrosine phosphatase non-receptor type 18).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6900525 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR016130 | Protein-tyrosine phosphatase, active site |
| Domain | IPR000242 | Tyrosine-specific protein phosphatase, PTPase domain |
| Domain | IPR000387 | Tyrosine-specific protein phosphatases domain |
| Domain | IPR003595 | Protein-tyrosine phosphatase, catalytic |
| Domain | IPR047254 | Tyrosine-protein phosphatase non-receptor type 18, catalytic domain |
| Family | IPR047170 | Tyrosine-protein phosphatase non-receptor type 12/18/22 |
| Homologous_superfamily | IPR029021 | Protein-tyrosine phosphatase-like |
Domain Details Per Protein
| Protein | Additional Resources | Length | Protein-tyrosine phosphatase, active site | Protein-tyrosine phosphatase, catalytic | Protein-tyrosine phosphatase-like | Tyrosine-protein phosphatase non-receptor type 12/18/22 | Tyrosine-protein phosphatase non-receptor type 18, catalytic domain | Tyrosine-specific protein phosphatase, PTPase domain | Tyrosine-specific protein phosphatases domain |
|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q5BJ20 | InterPro | 513 | |||||||
| UniProtKB:A0AB32TYG0 | InterPro | 514 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ptpn18-201
(1)
|
Ensembl | 2,386 nt | ||
| ncRNA |
ptpn18-002
(1)
|
Ensembl | 464 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers