Gene
pex7
- ID
- ZDB-GENE-050320-105
- Name
- peroxisomal biogenesis factor 7
- Symbol
- pex7 Nomenclature History
- Previous Names
-
- zgc:103552
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have peroxisome matrix targeting signal-2 binding activity. Predicted to be involved in protein import into peroxisome matrix. Predicted to localize to cytosol and peroxisomal matrix. Human ortholog(s) of this gene implicated in peroxisomal biogenesis disorder and rhizomelic chondrodysplasia punctata type 1. Orthologous to human PEX7 (peroxisomal biogenesis factor 7).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:103552 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Peroxisome biogenesis disorder 9B | Alliance | Peroxisome biogenesis disorder 9B | 614879 |
rhizomelic chondrodysplasia punctata type 1 | Alliance | Rhizomelic chondrodysplasia punctata, type 1 | 215100 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR019775 | WD40 repeat, conserved site |
Family | IPR044536 | Peroxisomal targeting signal 2 receptor |
Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
Repeat | IPR001680 | WD40 repeat |
Repeat | IPR020472 | G-protein beta WD-40 repeat |
Domain Details Per Protein
Protein | Length | G-protein beta WD-40 repeat | Peroxisomal targeting signal 2 receptor | WD40 repeat | WD40 repeat, conserved site | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
---|---|---|---|---|---|---|---|
UniProtKB:Q5BKX2
|
314 |
Interactions and Pathways
No data available
Plasmids
No data available