Gene

vipr1b

ID

ZDB-GENE-050311-6

Name

vasoactive intestinal peptide receptor 1b

Symbol

vipr1b Nomenclature History

Previous Names

vipr1
VPAC1 (1)
vpac1 receptor (1)
VPAC1R (1)

Type

protein_coding_gene

Location

Chr: 24 Mapping Details/Browsers

Description

Predicted to enable G protein-coupled peptide receptor activity; peptide hormone binding activity; and vasoactive intestinal polypeptide receptor activity. Acts upstream of or within adenylate cyclase-modulating G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including eye; gut; heart; integument; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in achalasia. Orthologous to human VIPR1 (vasoactive intestinal peptide receptor 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With vipr1b Human Ortholog

No data available

Associated With vipr1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017983	GPCR, family 2, secretin-like, conserved site
Domain	IPR001879	GPCR, family 2, extracellular hormone receptor domain
Domain	IPR017981	GPCR, family 2-like, 7TM
Family	IPR000832	GPCR, family 2, secretin-like
Family	IPR001771	GPCR, family 2, vasoactive intestinal peptide receptor 1
Family	IPR050332	G-protein coupled receptor 2
Homologous_superfamily	IPR036445	GPCR family 2, extracellular hormone receptor domain superfamily