ZFIN ID: ZDB-GENE-050309-27
Gene Name: ladybird homeobox 1b
Gene Symbol: lbx1b    Nomenclature History

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Previous Names: lbx1, lbx1a (1), im:7139117

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in convergent extension and regulation of Wnt signaling pathway. Predicted to localize to nucleus. Is expressed in nervous system; neural plate; neural tube; pectoral fin; and spinal cord neural keel. Orthologous to human LBX1 (ladybird homeobox 1).
Genome Resources: Alliance (1),  Gene:793810 (1),  Ensembl(GRCz11):ENSDARG00000018611 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hu3534 Point Mutation Unknown Premature Stop ENU
ko10 Indel Exon 1 Frameshift, Premature Stop TALEN
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
TALEN1-lbx1b 1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH lbx1b HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH lbx1b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process convergent extension (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA lbx1b-201 (1)    Ensembl 1619
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM lbx1b
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
Tg(lbx1b-gata2a:lbx1b,myl7:EGFP) gata2albx1bmyl7 EGFPlbx1b Danio rerio 1 1
Tg(lbx1b:EGFP) lbx1b EGFP Danio rerio 1 2
Tg(lbx1b:Tomato) lbx1b Tomato Danio rerio 1 2
Tg(UAS:lbx1b-EGFP,myl7:EGFP) myl7UAS EGFPlbx1b Danio rerio 1 1
MARKER RELATIONSHIPS
lbx1b Contained in: [BAC] DKEY-147L18 (1) (order this), DKEY-179O14 (1) (order this)
lbx1b Encodes: [EST] IMAGE:7139117 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001163312 (1) 1499 nt
Genomic GenBank:CT573247 (1) 107750 nt
Select Tool
Polypeptide UniProtKB:E7FDX5 (1) 265 aa
Sequence Information (all 10)
ORTHOLOGY for lbx1b ( Chr: 1 )
CITATIONS (27)