ZFIN ID: ZDB-GENE-050309-170
Gene Name: adenylate kinase 7b
Gene Symbol: ak7b    Nomenclature History

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Previous Names: im:7150989, zgc:165635

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Predicted to have ATP binding activity; adenylate kinase activity; and cytidylate kinase activity. Predicted to be involved in nucleobase-containing compound metabolic process and phosphorylation. Human ortholog(s) of this gene implicated in male infertility. Is expressed in nervous system; neural tube; and pronephric duct. Orthologous to human AK7 (adenylate kinase 7).
Genome Resources: Alliance (1),  Gene:504040 (1),  Ensembl(GRCz11):ENSDARG00000017023 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa23041 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ak7b HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    ?Spermatogenic failure 27 617965
    DISEASE ASSOCIATED WITH ak7b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process nucleobase-containing compound metabolic process (more)
    Cellular Component cellular_component (more)
    Molecular Function adenylate kinase activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Family IPR000850 Adenylate kinase/UMP-CMP kinase
    Conserved_site IPR007858 Dpy-30 motif
    Family IPR026867 Adenylate kinase 7
    Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
    Homologous_superfamily IPR036291 NAD(P)-binding domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ak7b-201 (1)    Ensembl 2453
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ak7b No data available
    MARKER RELATIONSHIPS
    ak7b Contained in: [BAC] DKEY-288A3 (1) (order this)
    ak7b Encodes: [EST] IMAGE:7150989 (1)
    [cDNA] MGC:165635 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001109698 (1) 2468 bp
    Genomic GenBank:CU571402 (1) 155030 bp
    Select Tool
    Polypeptide UniProtKB:A7MD66 (1) 699 aa
    Sequence Information (all 14)
    ORTHOLOGY for ak7b ( Chr: 17 )
    CITATIONS (19)