Gene
ak7b
- ID
- ZDB-GENE-050309-170
- Name
- adenylate kinase 7b
- Symbol
- ak7b Nomenclature History
- Previous Names
-
- im:7150989
- zgc:165635
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have ATP binding activity; adenylate kinase activity; and cytidylate kinase activity. Predicted to be involved in nucleobase-containing compound metabolic process and phosphorylation. Human ortholog(s) of this gene implicated in male infertility. Is expressed in nervous system; neural tube; and pronephric duct. Orthologous to human AK7 (adenylate kinase 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7150989 (15 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| spermatogenic failure 27 | Alliance | ?Spermatogenic failure 27 | 617965 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR007858 | Dpy-30 motif |
| Domain | IPR047499 | Adenylate kinase 7, dimerization/docking domain |
| Family | IPR000850 | Adenylate kinase/UMP-CMP kinase |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036291 | NAD(P)-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Adenylate kinase 7, dimerization/docking domain | Adenylate kinase/UMP-CMP kinase | Dpy-30 motif | NAD(P)-binding domain superfamily | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|
|
UniProtKB:F1QF80
|
699 |
Interactions and Pathways
No data available
Plasmids
No data available