Gene

mast2

ID

ZDB-GENE-050309-150

Name

microtubule associated serine/threonine kinase 2

Symbol

mast2 Nomenclature History

Previous Names

im:7150634

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to have protein serine/threonine kinase activity. Predicted to be involved in cytoskeleton organization; intracellular signal transduction; and peptidyl-serine phosphorylation. Predicted to localize to integral component of membrane. Orthologous to human MAST2 (microtubule associated serine/threonine kinase 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mast2 Human Ortholog

No data available

Associated With mast2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR008271	Serine/threonine-protein kinase, active site
Domain	IPR000719	Protein kinase domain
Domain	IPR000961	AGC-kinase, C-terminal
Domain	IPR001478	PDZ domain
Domain	IPR015022	Microtubule-associated serine/threonine-protein kinase, pre-PK domain
Domain	IPR037711	Microtubule-associated serine/threonine-protein kinase, catalytic domain
Domain	IPR041489	PDZ domain 6
Family	IPR050236	Serine/threonine-protein kinases, AGC
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily
Homologous_superfamily	IPR023142	Microtubule-associated serine/threonine-protein kinase, pre-PK domain superfamily
Homologous_superfamily	IPR036034	PDZ superfamily

Domain Details Per Protein

Protein	Length	AGC-kinase, C-terminal	Microtubule-associated serine/threonine-protein kinase, catalytic domain	Microtubule-associated serine/threonine-protein kinase, pre-PK domain	Microtubule-associated serine/threonine-protein kinase, pre-PK domain superfamily	PDZ domain	PDZ domain 6	PDZ superfamily	Protein kinase domain	Protein kinase-like domain superfamily	Serine/threonine-protein kinase, active site	Serine/threonine-protein kinases, AGC
UniProtKB:E7F723 InterPro	1934
UniProtKB:A0A8M1PUY5 InterPro	1927
UniProtKB:A0A8M9PYQ6 InterPro	1823
UniProtKB:A0A8M9PZC4 InterPro	1823
UniProtKB:A0A8M9P9A2 InterPro	1635
UniProtKB:A0A8M3ATG2 InterPro	1823
UniProtKB:A0A8M9PKF2 InterPro	1865
UniProtKB:A0A8M9Q232 InterPro	1824
UniProtKB:A0A8M9PRH1 InterPro	1858
UniProtKB:A0A8M2BDT3 InterPro	1824
UniProtKB:A0A8M9PMZ8 InterPro	1635
UniProtKB:A0A8M9Q5E7 InterPro	1866
UniProtKB:A0A8M9PTD2 InterPro	1824
UniProtKB:A0A8M9Q4J2 InterPro	224
UniProtKB:A0A8M9PGB4 InterPro	1865
UniProtKB:A0A8M9QAB0 InterPro	1873

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	mast2-201 (1) Ensembl	Ensembl	8,971 nt	Select Tool
mRNA	mast2-203 (1) Ensembl	Ensembl	2,310 nt	Select Tool ZFIN BLAST
mRNA	mast2-204 (1) Ensembl	Ensembl	1,344 nt	Select Tool ZFIN BLAST
ncRNA	mast2-002 (1) Ensembl	Ensembl	411 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations