Gene
msrab
- ID
- ZDB-GENE-050309-123
- Name
- methionine sulfoxide reductase Ab
- Symbol
- msrab Nomenclature History
- Previous Names
-
- im:7149628 (1)
- si:ch1073-358c10.1
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable L-methionine-(S)-S-oxide reductase activity and peptide-methionine (S)-S-oxide reductase activity. Predicted to be involved in cellular response to oxidative stress. Predicted to be located in membrane. Predicted to be active in cytoplasm. Orthologous to human MSRA (methionine sulfoxide reductase A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7149628 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| la020043Tg | Transgenic insertion | Unknown | Unknown | DNA | |
| sa42948 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| uab433 | Allele with multiple variants | Unknown | Unknown | CRISPR |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Methionine Sulfoxide Reductase A | Peptide methionine sulphoxide reductase MsrA domain | Peptide methionine sulphoxide reductase MsrA superfamily |
|---|---|---|---|---|
|
UniProtKB:F1R878
|
267 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:ch1073-358c10.1-201
(1)
|
Ensembl | 3,801 nt | ||
| mRNA |
si:ch1073-358c10.1-202
(1)
|
Ensembl | 499 nt | ||
| mRNA |
si:ch1073-358c10.1-203
(1)
|
Ensembl | 747 nt | ||
| mRNA |
si:ch1073-358c10.1-204
(1)
|
Ensembl | 778 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | Fosmid | CH1073-358C10 | ZFIN Curated Data | |
| Encodes | EST | IMAGE:7149628 | Thisse et al., 2004 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_009293138 (1) | 2052 nt | ||
| Genomic | GenBank:FP017192 (2) | 33752 nt | ||
| Polypeptide | UniProtKB:F1R878 (1) | 267 aa |
No data available
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Varshney, G.K., Lu, J., Gildea, D., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D.S., Pho, N., Casero, D., Hirase, T., Mosbrook-Davis, D.M., Zhang, S., Jao, L.E., Zhang, B., Woods, I.G., Zimmerman, S., Schier, A.F., Wolfsberg, T., Pellegrini, M., Burgess, S.M., and Lin, S. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research. 23(4):727-735
- Wang, D., Jao, L.E., Zheng, N., Dolan, K., Ivey, J., Zonies, S., Wu, X., Wu, K., Yang, H., Meng, Q., Zhu, Z., Zhang, B., Lin, S., and Burgess, S.M. (2007) Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proceedings of the National Academy of Sciences of the United States of America. 104(30):12428-12433
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