Gene

itsn2b

ID

ZDB-GENE-050309-102

Name

intersectin 2b

Symbol

itsn2b Nomenclature History

Previous Names

im:7149072 (1)
si:ch211-175f11.2 (1)

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Description

Predicted to have calcium ion binding activity and guanyl-nucleotide exchange factor activity. Predicted to be involved in endocytosis. Orthologous to human ITSN2 (intersectin 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7149072 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With itsn2b Human Ortholog

No data available

Associated With itsn2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR018247	EF-Hand 1, calcium-binding site
Domain	IPR000008	C2 domain
Domain	IPR000219	Dbl homology (DH) domain
Domain	IPR000261	EH domain
Domain	IPR001452	SH3 domain
Domain	IPR001849	Pleckstrin homology domain
Domain	IPR002048	EF-hand domain
Domain	IPR035740	Intersectin-2, fourth SH3 domain
Family	IPR051480	Endocytic & GEF Adapter
Homologous_superfamily	IPR011992	EF-hand domain pair
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR035892	C2 domain superfamily
Homologous_superfamily	IPR035899	Dbl homology (DH) domain superfamily
Homologous_superfamily	IPR036028	SH3-like domain superfamily