Gene

agtr2

ID
ZDB-GENE-050306-56
Name
angiotensin II receptor, type 2
Symbol
agtr2 Nomenclature History
Previous Names
  • zgc:113016
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to enable angiotensin type II receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and inflammatory response. Predicted to act upstream of or within signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including cardiovascular system; gill; liver; pleuroperitoneal region; and posterior lateral plate mesoderm. Human ortholog(s) of this gene implicated in IgA glomerulonephritis; end stage renal disease; hypoglycemia; intellectual disability; and vesicoureteral reflux. Orthologous to human AGTR2 (angiotensin II receptor type 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
la024871TgTransgenic insertionUnknownUnknownDNA
sa40411Allele with one point mutationUnknownPremature StopENU
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Sequence Targeting Reagents
No data available
Human Disease
Associated With agtr2 Human Ortholog
No data available
Associated With agtr2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR017452 GPCR, rhodopsin-like, 7TM
Family IPR000248 Angiotensin II receptor family
Family IPR000276 G protein-coupled receptor, rhodopsin-like
Family IPR050119 C-C chemokine receptor type 1-9-like
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Domain Details Per Protein
Protein Additional Resources Length Angiotensin II receptor family C-C chemokine receptor type 1-9-like GPCR, rhodopsin-like, 7TM G protein-coupled receptor, rhodopsin-like
UniProtKB:Q5CZS2 InterPro 360
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 5
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA agtr2-201 (1) Ensembl 1,875 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-125I10ZFIN Curated Data
EncodesESTIMAGE:6895796Thisse et al., 2004
EncodescDNAMGC:113016ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanAGTR2X
Amino acid sequence comparison (2)
Conserved genome location (synteny) (1)
MouseAgtr2X
Amino acid sequence comparison (1)
Citations
1 - 10 of 14
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