Gene

rfc2

ID

ZDB-GENE-050306-29

Name

replication factor C (activator 1) 2

Symbol

rfc2 Nomenclature History

Previous Names

zgc:110810

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Description

Predicted to contribute to DNA clamp loader activity. Predicted to be involved in DNA repair and DNA-dependent DNA replication. Predicted to localize to DNA replication factor C complex and nucleus. Is expressed in several structures, including alar plate midbrain region; central nervous system; digestive system; eye; and immature eye. Orthologous to human RFC2 (replication factor C subunit 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6902058 (9 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rfc2 Human Ortholog

No data available

Associated With rfc2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003593	AAA+ ATPase domain
Domain	IPR003959	ATPase, AAA-type, core
Domain	IPR013748	Replication factor C, C-terminal
Domain	IPR047854	Replication factor C, lid domain
Family	IPR050238	DNA Replication and Repair Clamp Loader Complex
Homologous_superfamily	IPR008921	DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase