ZFIN is now using GRCz12tu for Genomic Data
        
        
        Gene
fbxl22
- ID
- ZDB-GENE-050227-1
- Name
- F-box and leucine-rich repeat protein 22
- Symbol
- fbxl22 Nomenclature History
- Previous Names
- 
    
        
    
    
        
        - zgc:110743
 
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable cysteine-type deubiquitinase activity. Acts upstream of or within SCF-dependent proteasomal ubiquitin-dependent protein catabolic process and regulation of cardiac muscle cell contraction. Orthologous to human FBXL22 (F-box and leucine rich repeat protein 22).
- Genome Resources
- Note
- None
- Comparative Information
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- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
                
                    
                        Wild Type Expression Summary
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    - All Phenotype Data
- 3 figures from Spaich et al., 2012
- Cross-Species Comparison
- Alliance
                
                    
                        Phenotype Summary
                    
                    
                
                
            
        
        
    
        
            
                
            
        
    
    
    
                
                    
                        Mutations
                    
                    
                
                
            
        
        
    
        
            
            
    
    
                
                    
                        Human Disease
                    
                    
                
                
            
        
        
    
        
            
            
    
    
                
                    
                        Domain, Family, and Site Summary
                    
                    
                
                
            
        
        
    
        
            
                
    
        
    
    
    
            
        
    
    
    
                
                    
                        Domain Details Per Protein
                    
                    
                
                
            
        
        
    
        
            
                
    
        
    | Protein | Additional Resources | Length | F-box domain | F-box/Leucine-rich repeat | F-box-like domain superfamily | Leucine-rich repeat, cysteine-containing subtype | Leucine-rich repeat domain superfamily | 
|---|---|---|---|---|---|---|---|
| UniProtKB:Q5EAS7 | InterPro | 227 | 
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis | 
|---|---|---|---|---|---|
| mRNA | fbxl22-201
                             (1) | Ensembl | 1,208 nt | 
                
                    
                        Interactions and Pathways
                    
                    
                
                
            
        
        
    
        
            
            
    
    
        
    
No data available
    
        
        
    
    
    
                
                    
                        Plasmids
                    
                    
                
                
            
        
        
    
        
            
            
    
    
        
    
No data available
    
        
        
    
    
    - Genome Browsers
