Gene

tcf7

ID
ZDB-GENE-050222-4
Name
transcription factor 7
Symbol
tcf7 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in pectoral fin development and spinal cord dorsal/ventral patterning. Predicted to localize to beta-catenin-TCF complex and nuclear chromatin. Is expressed in several structures, including dermal bone; nervous system; optic cup; pectoral fin bud; and prechordal plate. Orthologous to human TCF7 (transcription factor 7).
Genome Resources
Note
None
Expression
All Expression Data
20 figures from 14 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tcf7 Human Ortholog
No data available
Associated With tcf7 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR009071 High mobility group box domain
Domain IPR013558 CTNNB1 binding, N-teminal
Family IPR024940 Transcription factor TCF/LEF
Family IPR028785 Transcription factor 7
Homologous_superfamily IPR027397 Catenin binding domain superfamily
Homologous_superfamily IPR036910 High mobility group box domain superfamily
Domain Details Per Protein
Protein Length Catenin binding domain superfamily CTNNB1 binding, N-teminal High mobility group box domain High mobility group box domain superfamily Transcription factor 7 Transcription factor TCF/LEF
UniProtKB:F1RAG0 239
UniProtKB:F8W4S5 239
UniProtKB:B3DIS1 351
UniProtKB:F8W2J8 217
UniProtKB:Q5PU94 355
UniProtKB:A0A2R8QK61 333
UniProtKB:Q5PU93 355
UniProtKB:F8W5T7 235
UniProtKB:F1QZD5 267
UniProtKB:A0A2R8Q6H8 354
UniProtKB:A5A8K1 333
UniProtKB:X1WDF3 355
UniProtKB:Q5PU92 19
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations