Gene
gdf9
- ID
- ZDB-GENE-050221-7
- Name
- growth differentiation factor 9
- Symbol
- gdf9 Nomenclature History
- Previous Names
-
- zgc:123030
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to have cytokine activity. Involved in female sex determination. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in premature ovarian failure. Is expressed in fertilized egg; gonad; and immature gonad. Orthologous to human GDF9 (growth differentiation factor 9).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 18 figures from 12 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Chen et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| primary ovarian insufficiency 14 | Alliance | ?Premature ovarian failure 14 | 618014 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cystine-knot cytokine | Transforming growth factor beta, conserved site | Transforming growth factor-beta, C-terminal | Transforming growth factor-beta-related |
|---|---|---|---|---|---|
|
UniProtKB:Q5MD90
|
418 |
Interactions and Pathways
No data available
Plasmids
No data available