Gene

ext1c

ID

ZDB-GENE-050211-5

Name

exostoses (multiple) 1c

Symbol

ext1c Nomenclature History

Previous Names

fa93b07
wu:fa93b07
zgc:136662

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Description

Predicted to enable N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity and glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity. Predicted to be involved in heparan sulfate proteoglycan biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in Golgi apparatus. Is expressed in brain; fin; otic vesicle; retina; and somite. Orthologous to human EXTL1 (exostosin like glycosyltransferase 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7159691 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ext1c Human Ortholog

No data available

Associated With ext1c Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR015338	Glycosyl transferase 64 domain
Domain	IPR040911	Exostosin, GT47 domain
Family	IPR004263	Exostosin-like
Homologous_superfamily	IPR029044	Nucleotide-diphospho-sugar transferases