Gene

arhgef3

ID

ZDB-GENE-050208-773

Name

Rho guanine nucleotide exchange factor (GEF) 3

Symbol

arhgef3 Nomenclature History

Previous Names

si:ch211-258l4.8

Type

protein_coding_gene

Location

Chr: 22 Mapping Details/Browsers

Description

Predicted to have Rho guanyl-nucleotide exchange factor activity. Involved in myeloid cell development. Orthologous to human ARHGEF3 (Rho guanine nucleotide exchange factor 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Gieger et al., 2011
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With arhgef3 Human Ortholog

No data available

Associated With arhgef3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR001331	Guanine-nucleotide dissociation stimulator, CDC24, conserved site
Domain	IPR000219	Dbl homology (DH) domain
Domain	IPR001849	Pleckstrin homology domain
Domain	IPR044129	Rho guanine nucleotide exchange factor 3, PH domain
Family	IPR051480	Endocytic & GEF Adapter
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR035899	Dbl homology (DH) domain superfamily