Gene

rc3h1a

ID

ZDB-GENE-050208-702

Name

ring finger and CCCH-type domains 1a

Symbol

rc3h1a Nomenclature History

Previous Names

rc3h1
si:dkey-192m14.4

Type

protein_coding_gene

Location

Chr: 22 Mapping Details/Browsers

Description

Predicted to have mRNA 3'-UTR binding activity and metal ion binding activity. Predicted to be involved in posttranscriptional regulation of gene expression and regulation of T cell proliferation. Orthologous to human RC3H1 (ring finger and CCCH-type domains 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rc3h1a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		?Immune dysregulation and systemic hyperinflammation syndrome	618998

Associated With rc3h1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017907	Zinc finger, RING-type, conserved site
Domain	IPR000571	Zinc finger, CCCH-type
Domain	IPR001841	Zinc finger, RING-type
Domain	IPR041523	Roquin II
Domain	IPR048575	Roquin 1/2-like, ROQ domain
Family	IPR052249	Roquin domain-containing protein
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily	IPR036855	Zinc finger, CCCH-type superfamily

Domain Details Per Protein

Protein	Length	Roquin 1/2-like, ROQ domain	Roquin domain-containing protein	Roquin II	Zinc finger, CCCH-type	Zinc finger, CCCH-type superfamily	Zinc finger, RING/FYVE/PHD-type	Zinc finger, RING-type	Zinc finger, RING-type, conserved site
UniProtKB:Q1LV60 InterPro	1078
UniProtKB:B3DIY0 InterPro	1078

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	rc3h1a-201 (1) Ensembl	Ensembl	3,648 nt	Select Tool
mRNA	rc3h1a-202 (1) Ensembl	Ensembl	3,440 nt	Select Tool ZFIN BLAST
mRNA	rc3h1a-203 (1) Ensembl	Ensembl	3,539 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations