ZFIN is now using GRCz12tu for Genomic Data
Gene
ap3d1
- ID
- ZDB-GENE-050208-437
- Name
- adaptor related protein complex 3 subunit delta 1
- Symbol
- ap3d1 Nomenclature History
- Previous Names
-
- si:ch211-129c21.6
- wu:fj51g01
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Acts upstream of or within negative regulation of autophagy and regulation of melanocyte differentiation. Predicted to be part of AP-3 adaptor complex. Predicted to be active in endosome membrane; presynaptic endosome; and terminal bouton. Human ortholog(s) of this gene implicated in Hermansky-Pudlak syndrome. Orthologous to human AP3D1 (adaptor related protein complex 3 subunit delta 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 5 figures from Neuffer et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| ?Hermansky-Pudlak syndrome 10 | 617050 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR002553 | Clathrin/coatomer adaptor, adaptin-like, N-terminal |
| Domain | IPR010474 | AP-3 complex subunit delta domain, metazoa |
| Family | IPR017105 | Adaptor protein complex AP-3, delta subunit |
| Homologous_superfamily | IPR011989 | Armadillo-like helical |
| Homologous_superfamily | IPR016024 | Armadillo-type fold |
Domain Details Per Protein
| Protein | Additional Resources | Length | Adaptor protein complex AP-3, delta subunit | AP-3 complex subunit delta domain, metazoa | Armadillo-like helical | Armadillo-type fold | Clathrin/coatomer adaptor, adaptin-like, N-terminal |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3AXP5 | InterPro | 1270 | |||||
| UniProtKB:B7ZUU8 | InterPro | 1247 | |||||
| UniProtKB:A0A8M3AXQ0 | InterPro | 1252 | |||||
| UniProtKB:A0A8M3B5I6 | InterPro | 1262 | |||||
| UniProtKB:A0A8M3AM99 | InterPro | 1262 | |||||
| UniProtKB:A0A8M3AUQ6 | InterPro | 1243 | |||||
| UniProtKB:A0A8M3AUQ1 | InterPro | 1263 | |||||
| UniProtKB:A0A8M3AN10 | InterPro | 1254 | |||||
| UniProtKB:A0AB32TG16 | InterPro | 1255 | |||||
| UniProtKB:A0AB32THS2 | InterPro | 1261 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers