Gene
nocta
- ID
- ZDB-GENE-050208-306
- Name
- nocturnin a
- Symbol
- nocta Nomenclature History
- Previous Names
-
- ccrn4la
- im:7147903
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to enable 3'-5'-RNA exonuclease activity. Predicted to act upstream of or within circadian rhythm. Predicted to be located in cytoplasm. Orthologous to human NOCT (nocturnin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa14909 | Allele with one point mutation | Unknown | Splice Site | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | CCR4/nocturin mRNA turnover and transcription | Endonuclease/exonuclease/phosphatase | Endonuclease/exonuclease/phosphatase superfamily | Nocturnin, deadenylase domain |
|---|---|---|---|---|---|---|
| UniProtKB:E7F177 | InterPro | 432 | ||||
| UniProtKB:A0A8M2BGW4 | InterPro | 373 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-235E9 | ||
| Encodes | EST | IMAGE:7147903 | Thisse et al., 2004 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_695702 (1) | 3390 nt | ||
| Genomic | GenBank:AL929007 (1) | 187464 nt | ||
| Polypeptide | UniProtKB:E7F177 (1) | 432 aa |
- Peterson, E.A., Sun, J., Chen, X., Wang, J. (2024) Neutrophils facilitate the epicardial regenerative response after zebrafish heart injury. Developmental Biology. 508:93-106
- Madera, D., Alonso-Gómez, A., Delgado, M.J., Valenciano, A.I., Alonso-Gómez, Á.L. (2023) Gene Characterization of Nocturnin Paralogues in Goldfish: Full Coding Sequences, Structure, Phylogeny and Tissue Expression. International Journal of Molecular Sciences. 25(1):
- Osorio-Méndez, D., Miller, A., Begeman, I.J., Kurth, A., Hagle, R., Rolph, D., Dickson, A.L., Chen, C.H., Halloran, M., Poss, K.D., Kang, J. (2022) Voltage-gated sodium channel scn8a is required for innervation and regeneration of amputated adult zebrafish fins. Proceedings of the National Academy of Sciences of the United States of America. 119:e2200342119
- Barthelson, K., Baer, L., Dong, Y., Hand, M., Pujic, Z., Newman, M., Goodhill, G.J., Richards, R.I., Pederson, S.M., Lardelli, M. (2021) Zebrafish Chromosome 14 Gene Differential Expression in the fmr1hu2787 Model of Fragile X Syndrome. Frontiers in genetics. 12:625466
- Blanc, M., Antczak, P., Cousin, X., Grunau, C., Scherbak, N., Rüegg, J., Keiter, S.H. (2021) The insecticide permethrin induces transgenerational behavioral changes linked to transcriptomic and epigenetic alterations in zebrafish (Danio rerio). The Science of the total environment. 779:146404
- Pedersen, J.E., Bergqvist, C.A., Larhammar, D. (2019) Evolution of vertebrate nicotinic acetylcholine receptors. BMC Evolutionary Biology. 19:38
- Yang, X., Fu, J., Wei, X. (2017) Expression patterns of zebrafish nocturnin genes and the transcriptional activity of the frog nocturnin promoter in zebrafish rod photoreceptors.. Molecular Vision. 23:1039-1047
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
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