Gene
si:ch211-106h11.3
- ID
- ZDB-GENE-050208-296
- Name
- si:ch211-106h11.3
- Symbol
- si:ch211-106h11.3 Nomenclature History
- Previous Names
-
- im:7147687
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable heparin binding activity and integrin binding activity. Predicted to be involved in several processes, including cell adhesion; positive regulation of cell differentiation; and positive regulation of cell migration. Predicted to be located in extracellular region. Predicted to be active in extracellular matrix and extracellular space.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| la024355Tg | Transgenic insertion | Unknown | Unknown | DNA | |
| la024356Tg | Transgenic insertion | Unknown | Unknown | DNA |
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No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000867 | Insulin-like growth factor-binding protein, IGFBP |
| Domain | IPR001007 | VWFC domain |
| Domain | IPR006207 | Cystine knot, C-terminal |
| Domain | IPR006208 | Glycoprotein hormone subunit beta |
| Domain | IPR043973 | CCN, TSP1 domain |
| Family | IPR012395 | IGFBP-related, CNN |
| Family | IPR050941 | Cellular Communication Network Factor |
| Homologous_superfamily | IPR009030 | Growth factor receptor cysteine-rich domain superfamily |
| Homologous_superfamily | IPR036383 | Thrombospondin type-1 (TSP1) repeat superfamily |
| Repeat | IPR000884 | Thrombospondin type-1 (TSP1) repeat |
Domain Details Per Protein
| Protein | Additional Resources | Length | CCN, TSP1 domain | Cellular Communication Network Factor | Cystine knot, C-terminal | Glycoprotein hormone subunit beta | Growth factor receptor cysteine-rich domain superfamily | IGFBP-related, CNN | Insulin-like growth factor-binding protein, IGFBP | Thrombospondin type-1 (TSP1) repeat | Thrombospondin type-1 (TSP1) repeat superfamily | VWFC domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:F1Q5N9 | InterPro | 381 | ||||||||||
| UniProtKB:A0A8M9PQ39 | InterPro | 381 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:ch211-106h11.3-201
(1)
|
Ensembl | 1,146 nt | ||
| mRNA |
si:ch211-106h11.3-202
(1)
|
Ensembl | 1,152 nt |
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH73-193D8 | ZFIN Curated Data | |
| Contained in | BAC | CH73-264I18 | ZFIN Curated Data | |
| Contained in | BAC | CH211-106H11 | ZFIN Curated Data | |
| Encodes | EST | IMAGE:7147687 | Thisse et al., 2004 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_683442 (1) | 7831 nt | ||
| Genomic | GenBank:BX248081 (1) | 174325 nt | ||
| Polypeptide | UniProtKB:A0A8M9PQ39 (1) | 381 aa |
No data available
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Varshney, G.K., Lu, J., Gildea, D., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D.S., Pho, N., Casero, D., Hirase, T., Mosbrook-Davis, D.M., Zhang, S., Jao, L.E., Zhang, B., Woods, I.G., Zimmerman, S., Schier, A.F., Wolfsberg, T., Pellegrini, M., Burgess, S.M., and Lin, S. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research. 23(4):727-735
- Wang, D., Jao, L.E., Zheng, N., Dolan, K., Ivey, J., Zonies, S., Wu, X., Wu, K., Yang, H., Meng, Q., Zhu, Z., Zhang, B., Lin, S., and Burgess, S.M. (2007) Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proceedings of the National Academy of Sciences of the United States of America. 104(30):12428-12433
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