Gene

phip

ID

ZDB-GENE-050208-261

Name

pleckstrin homology domain interacting protein

Symbol

phip Nomenclature History

Previous Names

im:7147010 (1)
si:dkey-261l7.3 (1)

Type

protein_coding_gene

Location

Chr: 23 Mapping Details/Browsers

Description

Predicted to enable insulin receptor binding activity. Predicted to be involved in cytoskeleton organization; regulation of cell shape; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within insulin receptor signaling pathway. Predicted to be active in nucleus. Orthologous to human PHIP (pleckstrin homology domain interacting protein).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7147010 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With phip Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Chung-Jansen syndrome	617991

Associated With phip Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018359	Bromodomain, conserved site
Conserved_site	IPR019775	WD40 repeat, conserved site
Domain	IPR001487	Bromodomain
Family	IPR052060	Bromodomain and WD repeat-containing
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036322	WD40-repeat-containing domain superfamily
Homologous_superfamily	IPR036427	Bromodomain-like superfamily
Repeat	IPR001680	WD40 repeat

Domain Details Per Protein

Protein	Length	Bromodomain	Bromodomain and WD repeat-containing	Bromodomain, conserved site	Bromodomain-like superfamily	WD40 repeat	WD40 repeat, conserved site	WD40-repeat-containing domain superfamily	WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:A0A8M3B6B2 InterPro	1806
UniProtKB:A0A8M9PE61 InterPro	1806
UniProtKB:A0A8M2B991 InterPro	1635
UniProtKB:A0A8M3AN51 InterPro	1807
UniProtKB:A0A8M9PQW8 InterPro	1805

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	phip-201 (1) Ensembl	Ensembl	5,388 nt	Select Tool ZFIN BLAST
mRNA	phip-204 (1) Ensembl	Ensembl	5,486 nt	Select Tool ZFIN BLAST
ncRNA	phip-002 (1) Ensembl	Ensembl	446 nt	Select Tool ZFIN BLAST
ncRNA	phip-003 (1) Ensembl	Ensembl	536 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations