ZFIN is now using GRCz12tu for Genomic Data
Gene
edaradd
- ID
- ZDB-GENE-050114-5
- Name
- EDAR-associated death domain
- Symbol
- edaradd Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Is expressed in mouth. Human ortholog(s) of this gene implicated in ectodermal dysplasia 11A and ectodermal dysplasia 11B. Orthologous to human EDARADD (EDAR associated via death domain).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Aigler et al., 2014
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Sadier et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| ectodermal dysplasia 11A | Alliance | Ectodermal dysplasia 11A, hypohidrotic/hair/tooth type, autosomal dominant | 614940 |
| ectodermal dysplasia 11B | Alliance | Ectodermal dysplasia 11B, hypohidrotic/hair/tooth type, autosomal recessive | 614941 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Death domain | Death-like domain superfamily | Ectodysplasin-A receptor-associated adapter protein |
|---|---|---|---|---|---|
| UniProtKB:E7F388 | InterPro | 219 | |||
| UniProtKB:A0A8M9PYQ7 | InterPro | 193 | |||
| UniProtKB:A0AA70QGP6 | InterPro | 219 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
edaradd-201
(1)
|
Ensembl | 1,887 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers