Gene

edaradd

ID
ZDB-GENE-050114-5
Name
EDAR-associated death domain
Symbol
edaradd Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Involved in embryonic viscerocranium morphogenesis. Is expressed in mouth. Human ortholog(s) of this gene implicated in ectodermal dysplasia 11A and ectodermal dysplasia 11B. Orthologous to human EDARADD (EDAR associated death domain).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Aigler et al., 2014
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Sadier et al., 2015
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With edaradd Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
ectodermal dysplasia 11A Alliance Ectodermal dysplasia 11A, hypohidrotic/hair/tooth type, autosomal dominant 614940
ectodermal dysplasia 11B Alliance Ectodermal dysplasia 11B, hypohidrotic/hair/tooth type, autosomal recessive 614941
Associated With edaradd Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000488 Death domain
Family IPR039200 Ectodysplasin-A receptor-associated adapter protein
Homologous_superfamily IPR011029 Death-like domain superfamily
Domain Details Per Protein
Protein Length Death domain Death-like domain superfamily Ectodysplasin-A receptor-associated adapter protein
UniProtKB:E7F388 219
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations