Gene

lmx1ba

ID
ZDB-GENE-050114-3
Name
LIM homeobox transcription factor 1, beta a
Symbol
lmx1ba Nomenclature History
Previous Names
  • lmx1b.2
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in animal organ development and glutamatergic neuron differentiation. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in nail-patella syndrome. Is expressed in several structures, including axis; midbrain hindbrain boundary neural rod; midbrain neural rod; nervous system; and periocular mesenchyme. Orthologous to human LMX1B (LIM homeobox transcription factor 1 beta).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
17 figures from 11 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With lmx1ba Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
nail-patella syndrome Alliance Nail-patella syndrome 161200
Focal segmental glomerulosclerosis 10 256020
Associated With lmx1ba Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeodomain
Domain IPR001781 Zinc finger, LIM-type
Family IPR050453 LIM/homeobox transcription factors
Homologous_superfamily IPR009057 Homedomain-like superfamily
Domain Details Per Protein
Protein Length Homedomain-like superfamily Homeobox, conserved site Homeodomain LIM/homeobox transcription factors Zinc finger, LIM-type
UniProtKB:Q4VJ28 373
UniProtKB:Q4L1M5 375
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA lmx1ba-201 (1) Ensembl 2,057 nt
mRNA lmx1ba-202 (1) Ensembl 185 nt
mRNA lmx1ba-203 (1) Ensembl 1,128 nt
mRNA lmx1ba-204 (1) Ensembl 1,362 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations