Gene
ift27
- ID
- ZDB-GENE-041212-9
- Name
- intraflagellar transport 27 homolog (Chlamydomonas)
- Symbol
- ift27 Nomenclature History
- Previous Names
-
- rabl4
- zgc:101893
- Type
- protein_coding_gene
- Location
- Unmapped
- Description
- Predicted to enable GTP binding activity and GTPase activity. Acts upstream of or within cilium assembly; kidney development; and regulation of melanosome transport. Predicted to be part of intraciliary transport particle B. Predicted to be active in Golgi membrane and sperm flagellum. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome 19. Orthologous to human IFT27 (intraflagellar transport 27).
- Genome Resources
-
- Alliance (1)
- Gene:494045 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7148811 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Bardet-Biedl syndrome 19 | Alliance | Bardet-Biedl syndrome 19 | 615996 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Intraflagellar transport protein 27 homologue, eukaryotes | P-loop containing nucleoside triphosphate hydrolase | Small GTPase | Small GTP-binding domain |
|---|---|---|---|---|---|
|
UniProtKB:Q5PR92
|
186 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance