Gene
tm7sf2
- ID
- ZDB-GENE-041212-19
- Name
- transmembrane 7 superfamily member 2
- Symbol
- tm7sf2 Nomenclature History
- Previous Names
-
- zgc:103611 (1)
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable delta14-sterol reductase activity. Predicted to be involved in cholesterol biosynthetic process. Predicted to act upstream of or within cholesterol metabolic process and sterol biosynthetic process. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum membrane and nuclear inner membrane. Is expressed in central nervous system; gut; and liver. Orthologous to human TM7SF2 (transmembrane 7 superfamily member 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:103611 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Sterol biosynthesis ERG24/DHCR-like | Sterol reductase, conserved site |
|---|---|---|---|
|
UniProtKB:Q5PR41
|
421 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tm7sf2-201
(1)
|
Ensembl | 1,601 nt | ||
| mRNA |
tm7sf2-202
(1)
|
Ensembl | 1,050 nt | ||
| mRNA |
tm7sf2-204
(1)
|
Ensembl | 1,281 nt | ||
| ncRNA |
tm7sf2-003
(1)
|
Ensembl | 570 nt |
Interactions and Pathways
No data available
Plasmids
No data available