ZFIN is now using GRCz12tu for Genomic Data

Gene

aimp1b

ID

ZDB-GENE-041212-13

Name

aminoacyl tRNA synthetase complex interacting multifunctional protein 1b

Symbol

aimp1b Nomenclature History

Previous Names

zgc:101853

Type

protein_coding_gene

Location

Chr: 23 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable tRNA binding activity. Predicted to be involved in translation. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 3. Orthologous to human AIMP1 (aminoacyl tRNA synthetase complex interacting multifunctional protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Lin et al., 2021

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With aimp1b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
hypomyelinating leukodystrophy 3	Alliance	Leukodystrophy, hypomyelinating, 3	260600

Associated With aimp1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002547	tRNA-binding domain
Family	IPR051270	Tyrosine-tRNA ligase and regulatory protein
Homologous_superfamily	IPR012340	Nucleic acid-binding, OB-fold

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M9PKQ7	InterPro	346
UniProtKB:Q5PR96	InterPro	282
UniProtKB:A0A8M2BI20	InterPro	301
UniProtKB:A0AB32TCW9	InterPro	365
UniProtKB:A0AB32THP4	InterPro	301

Transcripts

Genome Browsers

NCBI Map Viewer

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
aberrant processed transcript	zgc:101853-202 (1) Ensembl	Ensembl	953 nt	Select Tool ZFIN BLAST
aberrant processed transcript	zgc:101853-203 (1) Ensembl	Ensembl	818 nt	Select Tool ZFIN BLAST
mRNA	zgc:101853-201 (1) Ensembl	Ensembl	818 nt	Select Tool ZFIN BLAST
mRNA	zgc:101853-204 (1) Ensembl	Ensembl	621 nt	Select Tool ZFIN BLAST
mRNA	zgc:101853-205 (1) Ensembl	Ensembl	1,145 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Genome Browsers

NCBI Map Viewer

ZFIN

Orthology

Comparative Orthology: Alliance

Citations