ZFIN ID: ZDB-GENE-041212-11
Gene Name: solute carrier family 35 member C1
Gene Symbol: slc35c1    Nomenclature History

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Previous Names: fc03b12, GFT (1), wu:fc03b12 (1), zgc:101867 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have GDP-fucose transmembrane transporter activity and antiporter activity. Predicted to be involved in GDP-fucose import into Golgi lumen and protein O-linked fucosylation. Predicted to localize to the Golgi apparatus. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIc. Orthologous to human SLC35C1 (solute carrier family 35 member C1).
Genome Resources: Alliance (1),  Gene:494047 (1),  Ensembl(GRCz11):ENSDARG00000104669 (1)
GENE EXPRESSION
All Expression Data: 4 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:101867]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 4 (96.0h-120.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-slc35c1 N/A 1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH slc35c1 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
congenital disorder of glycosylation type IIc Alliance Congenital disorder of glycosylation, type IIc 266265
DISEASE ASSOCIATED WITH slc35c1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process GDP-fucose import into Golgi lumen (more)
Cellular Component Golgi apparatus (more)
Molecular Function GDP-fucose transmembrane transporter activity (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR004853 Sugar phosphate transporter domain
Family IPR029666 GDP-fucose transporter
TRANSCRIPTS No data available
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM slc35c1 No data available
MARKER RELATIONSHIPS
slc35c1 Encodes: [EST] fc03b12
[cDNA] MGC:101867 (1), MGC:173743 (1), MGC:191337 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001008590 (1)
Polypeptide UniProtKB:A8WGL3 (1) 348 aa
Sequence Information (all 21)
ORTHOLOGY for slc35c1 ( Chr: 7 )
CITATIONS (20)