Gene

fbxo18

ID
ZDB-GENE-041210-99
Name
F-box DNA helicase 1
Symbol
fbxo18 Nomenclature History
Previous Names
  • si:dkey-22l11.2
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to enable 3'-5' DNA helicase activity. Predicted to be involved in double-strand break repair via homologous recombination and replication fork processing. Predicted to be active in nucleus. Orthologous to human FBH1 (F-box DNA helicase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa9000Allele with one point mutationUnknownPremature StopENU
European Zebrafish Resource Center (EZRC) (order this)
Zebrafish International Resource Center (ZIRC) (order this)
sa33396Allele with one point mutationUnknownPremature StopENU
Zebrafish International Resource Center (ZIRC) (order this)
European Zebrafish Resource Center (EZRC) (order this)
sa40228Allele with one point mutationUnknownPremature StopENU
Zebrafish International Resource Center (ZIRC) (order this)
European Zebrafish Resource Center (EZRC) (order this)
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Sequence Targeting Reagents
No data available
Human Disease
Associated With fbxo18 Human Ortholog
No data available
Associated With fbxo18 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001810 F-box domain
Domain IPR014016 UvrD-like helicase, ATP-binding domain
Domain IPR014017 UvrD-like DNA helicase, C-terminal
Family IPR000212 DNA helicase, UvrD/REP type
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
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Domain Details Per Protein
Protein Additional Resources Length DNA helicase, UvrD/REP type F-box domain F-box-like domain superfamily P-loop containing nucleoside triphosphate hydrolase UvrD-like DNA helicase, C-terminal UvrD-like helicase, ATP-binding domain
UniProtKB:A0A8M9PHI1 InterPro 1010
UniProtKB:A0A8M6Z5E0 InterPro 1009
UniProtKB:A0A8M3B1M6 InterPro 1011
UniProtKB:E9QBZ9 InterPro 992
UniProtKB:A0AB32TPL7 InterPro 965
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 4
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA fbxo18-201 (1)
Ensembl
Ensembl 3,002 nt
ZFIN BLAST
mRNA fbxo18-202 (1)
Ensembl
Ensembl 3,377 nt
ZFIN BLAST
mRNA fbxo18-203 (1)
Ensembl
Ensembl 5,834 nt
ZFIN BLAST
mRNA fbxo18-204 (1)
Ensembl
Ensembl 5,766 nt
ZFIN BLAST
mRNA fbxo18-205 (1)
Ensembl
Ensembl 5,982 nt
ZFIN BLAST
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-22L11ZFIN Curated Data
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Sequences
Type Accession # Sequence Length (nt/aa) Analysis
RNARefSeq:NM_001045149 (1)3002 nt
ZFIN BLASTNCBI BLASTEnsemblUCSC BLAT
GenomicGenBank:BX465859 (1)214205 nt
MegaBLAST
PolypeptideUniProtKB:A0A8M3B1M6 (1)1011 aa
ZFIN BLASTSIB BLASTEnsembl Protein Blast
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanFBH110
Amino acid sequence comparison (1)
MouseFbh12
Amino acid sequence comparison (1)
Citations
No data available
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