Gene
ada2b
- ID
- ZDB-GENE-041210-77
- Name
- adenosine deaminase 2b
- Symbol
- ada2b Nomenclature History
- Previous Names
-
- ADA2-2 (1)
- cecr1b
- si:ch211-214j24.5
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to enable adenosine deaminase activity. Acts upstream of or within blood vessel endothelial cell differentiation and neutrophil differentiation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including cardiovascular system; gill; liver; notochord; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in Sneddon syndrome. Orthologous to human ADA2 (adenosine deaminase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Sneddon syndrome | Alliance | Sneddon syndrome | 182410 |
| Vasculitis, autoinflammation, immunodeficiency, and hematologic defects syndrome | 615688 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Adenosine/adenine deaminase | Adenosine/AMP deaminase N-terminal | Adenosine deaminase domain | Adenosine deaminase-related growth factor | Metal-dependent hydrolase |
|---|---|---|---|---|---|---|
|
UniProtKB:F6NKG5
|
501 |
Interactions and Pathways
No data available
Plasmids
No data available