Gene
gak
- ID
- ZDB-GENE-041210-358
- Name
- cyclin G associated kinase
- Symbol
- gak Nomenclature History
- Previous Names
-
- si:dkeyp-1e8.1
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have clathrin binding activity. Predicted to be involved in clathrin coat disassembly and clathrin-dependent endocytosis. Localizes to cytosol and perinuclear region of cytoplasm. Is expressed in brain; eye; immature eye; otic vesicle; and vasculature. Orthologous to human GAK (cyclin G associated kinase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Bai et al., 2010
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Bai et al., 2010
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR001623 | DnaJ domain |
| Domain | IPR014020 | Tensin phosphatase, C2 domain |
| Domain | IPR029023 | Tensin-type phosphatase domain |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR029021 | Protein-tyrosine phosphatase-like |
| Homologous_superfamily | IPR035892 | C2 domain superfamily |
| Homologous_superfamily | IPR036869 | Chaperone J-domain superfamily |
Domain Details Per Protein
| Protein | Length | C2 domain superfamily | Chaperone J-domain superfamily | DnaJ domain | Protein kinase domain | Protein kinase-like domain superfamily | Protein-tyrosine phosphatase-like | Serine/threonine-protein kinase, active site | Tensin phosphatase, C2 domain | Tensin-type phosphatase domain |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3B9D0
|
1280 | |||||||||
|
UniProtKB:A0A8M3B270
|
1264 | |||||||||
|
UniProtKB:A0A0R4IWM3
|
1278 |
Interactions and Pathways
No data available
Plasmids
No data available