Gene
mfsd2b
- ID
- ZDB-GENE-041210-308
- Name
- MFSD2 lysolipid transporter B, sphingolipid
- Symbol
- mfsd2b Nomenclature History
- Previous Names
-
- si:dkeyp-115a10.4
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable sphingolipid transporter activity. Predicted to be involved in lipid transport and transmembrane transport. Predicted to act upstream of or within carbohydrate transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human MFSD2B (MFSD2 lysolipid transporter B, sphingolipid).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Lactose permease-like | MFS transporter superfamily |
|---|---|---|---|---|
| UniProtKB:A0A0R4J720 | InterPro | 551 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
mfsd2b-201
(1)
|
Ensembl | 1,476 nt | ||
| mRNA |
mfsd2b-202
(1)
|
Ensembl | 2,090 nt |
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEYP-115A10 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001365964 (1) | |||
| Genomic | GenBank:CR545466 (1) | 84525 nt | ||
| Polypeptide | UniProtKB:A0A0R4J720 (1) | 551 aa |
- Perland, E., Bagchi, S., Klaesson, A., Fredriksson, R. (2017) Characteristics of 29 novel atypical solute carriers of major facilitator superfamily type: evolutionary conservation, predicted structure and neuronal co-expression. Open Biology. 7(9)
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
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