Gene
stxbp5l
- ID
- ZDB-GENE-041210-220
- Name
- syntaxin binding protein 5L
- Symbol
- stxbp5l Nomenclature History
- Previous Names
-
- si:ch211-194d6.1
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to enable GTPase activator activity; myosin II binding activity; and syntaxin binding activity. Predicted to be involved in Golgi to plasma membrane transport and exocytosis. Predicted to act upstream of or within protein transport. Predicted to be located in membrane. Predicted to be part of SNARE complex. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human STXBP5L (syntaxin binding protein 5L).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa2514 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa31716 | Allele with one point mutation | Unknown | Premature Stop | ENU | |
| sa34659 | Allele with one point mutation | Unknown | Splice Site | ENU | |
| sa34660 | Allele with one point mutation | Unknown | Splice Site | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR013577 | Lethal giant larvae homologue 2 |
| Domain | IPR042855 | v-SNARE, coiled-coil homology domain |
| Family | IPR000664 | Lethal(2) giant larvae protein |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
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Domain Details Per Protein
| Protein | Additional Resources | Length | Lethal(2) giant larvae protein | Lethal giant larvae homologue 2 | v-SNARE, coiled-coil homology domain | WD40 repeat | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9QAW6 | InterPro | 1120 | ||||||
| UniProtKB:A0A8M2BF49 | InterPro | 1249 | ||||||
| UniProtKB:A0A8M9QJS6 | InterPro | 1097 | ||||||
| UniProtKB:A0A2R8Q0L1 | InterPro | 1158 | ||||||
| UniProtKB:Q5SQE2 | InterPro | 1159 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
stxbp5l-201
(1)
|
Ensembl | 3,908 nt | ||
| mRNA |
stxbp5l-202
(1)
|
Ensembl | 643 nt | ||
| mRNA |
stxbp5l-203
(1)
|
Ensembl | 4,269 nt | ||
| mRNA |
stxbp5l-204
(1)
|
Ensembl | 4,200 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-194D6 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-22A1 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-193N17 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-283D12 | ZFIN Curated Data | |
| Contained in | BAC | RP71-86I11 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001045137 (1) | 3480 nt | ||
| Genomic | GenBank:AL772198 (1) | 211682 nt | ||
| Polypeptide | UniProtKB:A0A8M2BF64 (1) | 1267 aa |
- Eachus, H., Oberski, L., Paveley, J., Bacila, I., Ashton, J.P., Esposito, U., Seifuddin, F., Pirooznia, M., Elhaik, E., Placzek, M., Krone, N., Cunliffe, V.T. (2023) Glucocorticoid Receptor regulates protein chaperone, circadian clock and affective disorder genes in the zebrafish brain. Disease models & mechanisms. 16(9):
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Coppola, U., Annona, G., D'Aniello, S., Ristoratore, F. (2016) Rab32 and Rab38 genes in chordate pigmentation: an evolutionary perspective. BMC Evolutionary Biology. 16:26
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