Gene
nuak1a
- ID
- ZDB-GENE-041210-122
- Name
- NUAK family, SNF1-like kinase, 1a
- Symbol
- nuak1a Nomenclature History
- Previous Names
-
- si:dkey-261e22.1
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to enable protein serine/threonine kinase activity. Predicted to act upstream of or within protein phosphorylation. Is expressed in ventral mesoderm. Human ortholog(s) of this gene implicated in uterine fibroid. Orthologous to human NUAK1 (NUAK family kinase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Kimelman et al., 2017
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|
| UniProtKB:F1R343 | InterPro | 617 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nuak1a-201
(1)
|
Ensembl | 2,124 nt |
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-261E22 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_684974 (1) | 4144 nt | ||
| Genomic | GenBank:BX571705 (1) | 143674 nt | ||
| Polypeptide | UniProtKB:F1R343 (1) | 617 aa |
- Jiang, P., Hou, Y., Fu, W., Tao, X., Luo, J., Lu, H., Xu, Y., Han, B., Zhang, J. (2018) Characterization of lncRNAs involved in cold acclimation of zebrafish ZF4 cells. PLoS One. 13:e0195468
- Kimelman, D., Smith, N.L., Lai, J.K.H., Stainier, D.Y. (2017) Regulation of posterior body and epidermal morphogenesis in Zebrafish by localized Yap1 and Wwtr1. eLIFE. 6
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Haug, M.F., Gesemann, M., Lazovic, V., Neuhauss, S.C. (2015) Eumetazoan Cryptochrome Phylogeny and Evolution. Genome biology and evolution. 7(2):601-19
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