Gene
clic5a
- ID
- ZDB-GENE-041114-84
- Name
- chloride intracellular channel 5a
- Symbol
- clic5a Nomenclature History
- Previous Names
-
- clic5al (1)
- zgc:101827
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have chloride channel activity. Predicted to be involved in chloride transport and regulation of ion transmembrane transport. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 103. Orthologous to human CLIC5 (chloride intracellular channel 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive nonsyndromic deafness 103 | Alliance | ?Deafness, autosomal recessive 103 | 616042 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR010987 | Glutathione S-transferase, C-terminal-like |
| Domain | IPR042069 | CLIC5, C-terminal GST domain |
| Domain | IPR053823 | CLIC, N-terminal domain |
| Family | IPR002946 | Intracellular chloride channel |
| Family | IPR040079 | Glutathione transferase family |
| Homologous_superfamily | IPR036249 | Thioredoxin-like superfamily |
| Homologous_superfamily | IPR036282 | Glutathione S-transferase, C-terminal domain superfamily |
Domain Details Per Protein
| Protein | Length | CLIC5, C-terminal GST domain | CLIC, N-terminal domain | Glutathione S-transferase, C-terminal domain superfamily | Glutathione S-transferase, C-terminal-like | Glutathione transferase family | Intracellular chloride channel | Thioredoxin-like superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q5U3P5
|
246 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
clic5a-201
(1)
|
Ensembl | 1,906 nt |
Interactions and Pathways
No data available
Plasmids
No data available