Gene

cetp

ID
ZDB-GENE-041114-54
Name
cholesteryl ester transfer protein, plasma
Symbol
cetp Nomenclature History
Previous Names
  • zgc:103675
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to enable several functions, including cholesterol binding activity; phosphatidylcholine binding activity; and triglyceride binding activity. Predicted to be involved in several processes, including glycerolipid metabolic process; lipid homeostasis; and plasma lipoprotein particle remodeling. Predicted to act upstream of or within reverse cholesterol transport and steroid metabolic process. Predicted to be located in extracellular region. Predicted to be part of high-density lipoprotein particle. Is expressed in asteriscus; liver; otic vesicle; and yolk syncytial layer. Human ortholog(s) of this gene implicated in carotid artery disease and hyperalphalipoproteinemia 1. Orthologous to human CETP (cholesteryl ester transfer protein).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cetp Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hyperalphalipoproteinemia 1 Alliance Hyperalphalipoproteinemia 143470
hyperalphalipoproteinemia 1 Alliance [High density lipoprotein cholesterol level QTL 10] 143470
Associated With cetp Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001124 Lipid-binding serum glycoprotein, C-terminal
Domain IPR017942 Lipid-binding serum glycoprotein, N-terminal
Family IPR017130 Cholesteryl ester transfer
Homologous_superfamily IPR017943 Bactericidal permeability-increasing protein, alpha/beta domain superfamily
Domain Details Per Protein
Protein Length Bactericidal permeability-increasing protein, alpha/beta domain superfamily Cholesteryl ester transfer Lipid-binding serum glycoprotein, C-terminal Lipid-binding serum glycoprotein, N-terminal
UniProtKB:Q5U3E2 493
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations