Gene

cetp

ID

ZDB-GENE-041114-54

Name

cholesteryl ester transfer protein, plasma

Symbol

cetp Nomenclature History

Previous Names

zgc:103675

Type

protein_coding_gene

Location

Chr: 18 Mapping Details/Browsers

Description

Predicted to have several functions, including cholesterol binding activity; phosphatidylcholine binding activity; and triglyceride binding activity. Predicted to be involved in several processes, including glycerolipid metabolic process; lipid homeostasis; and plasma lipoprotein particle remodeling. Predicted to localize to high-density lipoprotein particle. Human ortholog(s) of this gene implicated in carotid artery disease and hyperalphalipoproteinemia 1. Is expressed in asteriscus; liver; otic vesicle; and yolk syncytial layer. Orthologous to human CETP (cholesteryl ester transfer protein).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

11 figures from 5 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7158433 (8 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cetp Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
hyperalphalipoproteinemia 1	Alliance	Hyperalphalipoproteinemia	143470
hyperalphalipoproteinemia 1	Alliance	[High density lipoprotein cholesterol level QTL 10]	143470

Associated With cetp Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001124	Lipid-binding serum glycoprotein, C-terminal
Domain	IPR017942	Lipid-binding serum glycoprotein, N-terminal
Family	IPR017130	Cholesteryl ester transfer
Homologous_superfamily	IPR017943	Bactericidal permeability-increasing protein, alpha/beta domain superfamily