Gene
cetp
- ID
- ZDB-GENE-041114-54
- Name
- cholesteryl ester transfer protein, plasma
- Symbol
- cetp Nomenclature History
- Previous Names
-
- zgc:103675
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to have several functions, including cholesterol binding activity; phosphatidylcholine binding activity; and triglyceride binding activity. Predicted to be involved in several processes, including glycerolipid metabolic process; lipid homeostasis; and plasma lipoprotein particle remodeling. Predicted to localize to high-density lipoprotein particle. Is expressed in asteriscus; liver; otic vesicle; and yolk syncytial layer. Human ortholog(s) of this gene implicated in carotid artery disease and hyperalphalipoproteinemia 1. Orthologous to human CETP (cholesteryl ester transfer protein).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 11 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7158433 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
hyperalphalipoproteinemia 1 | Alliance | Hyperalphalipoproteinemia | 143470 |
hyperalphalipoproteinemia 1 | Alliance | [High density lipoprotein cholesterol level QTL 10] | 143470 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Bactericidal permeability-increasing protein, alpha/beta domain superfamily | Cholesteryl ester transfer | Lipid-binding serum glycoprotein, C-terminal | Lipid-binding serum glycoprotein, N-terminal |
---|---|---|---|---|---|
UniProtKB:A0A8M3ARX3
|
518 | ||||
UniProtKB:Q5U3E2
|
493 |
Interactions and Pathways
No data available
Plasmids
No data available