Gene

cetp

ID

ZDB-GENE-041114-54

Name

cholesteryl ester transfer protein, plasma

Symbol

cetp Nomenclature History

Previous Names

zgc:103675

Type

protein_coding_gene

Location

Chr: 18 Mapping Details/Browsers

Description

Predicted to enable several functions, including cholesterol binding activity; phosphatidylcholine binding activity; and triglyceride binding activity. Predicted to be involved in several processes, including cholesterol homeostasis; glycerolipid metabolic process; and plasma lipoprotein particle remodeling. Predicted to act upstream of or within reverse cholesterol transport and steroid metabolic process. Predicted to be located in extracellular region. Predicted to be part of high-density lipoprotein particle. Is expressed in asteriscus; liver; otic vesicle; and yolk syncytial layer. Human ortholog(s) of this gene implicated in carotid artery disease and hyperalphalipoproteinemia 1. Orthologous to human CETP (cholesteryl ester transfer protein).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

11 figures from 5 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7158433 (8 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cetp Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
hyperalphalipoproteinemia 1	Alliance	Hyperalphalipoproteinemia	143470
hyperalphalipoproteinemia 1	Alliance	[High density lipoprotein cholesterol level QTL 10]	143470

Associated With cetp Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001124	Lipid-binding serum glycoprotein, C-terminal
Domain	IPR017942	Lipid-binding serum glycoprotein, N-terminal
Family	IPR017130	Cholesteryl ester transfer
Homologous_superfamily	IPR017943	Bactericidal permeability-increasing protein, alpha/beta domain superfamily