ZFIN is now using GRCz12tu for Genomic Data
Gene
spire2
- ID
- ZDB-GENE-041114-29
- Name
- spire-type actin nucleation factor 2
- Symbol
- spire2 Nomenclature History
- Previous Names
-
- zgc:103506 (1)
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable microtubule binding activity. Predicted to be involved in several processes, including cytoskeleton organization; cytoskeleton-dependent cytokinesis; and positive regulation of double-strand break repair. Predicted to be located in plasma membrane. Predicted to be active in cell cortex and cytoplasmic vesicle membrane. Orthologous to human SPIRE2 (spire type actin nucleation factor 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:103506 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | KIND domain | Protein Spire | WH2 domain | Zinc finger, FYVE/PHD-type |
|---|---|---|---|---|---|---|
| UniProtKB:E7EZ28 | InterPro | 730 | ||||
| UniProtKB:Q5U3H9 | InterPro | 606 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
spire2-201
(1)
|
Ensembl | 1,314 nt | ||
| mRNA |
spire2-202
(1)
|
Ensembl | 3,749 nt | ||
| mRNA |
spire2-203
(1)
|
Ensembl | 2,131 nt | ||
| mRNA |
spire2-204
(1)
|
Ensembl | 2,181 nt | ||
| mRNA |
spire2-205
(1)
|
Ensembl | 2,722 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers