Gene
spire2
- ID
- ZDB-GENE-041114-29
- Name
- spire-type actin nucleation factor 2
- Symbol
- spire2 Nomenclature History
- Previous Names
-
- zgc:103506 (1)
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to have actin binding activity. Predicted to be involved in formin-nucleated actin cable assembly and positive regulation of double-strand break repair. Predicted to localize to several cellular components, including cytoplasmic vesicle membrane; cytoskeleton; and cytosol. Orthologous to human SPIRE2 (spire type actin nucleation factor 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:103506 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | KIND domain | Protein Spire | WH2 domain | Zinc finger, FYVE/PHD-type |
|---|---|---|---|---|---|
|
UniProtKB:E7EZ28
|
730 | ||||
|
UniProtKB:Q5U3H9
|
606 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
spire2-201
(1)
|
Ensembl | 1,314 nt | ||
| mRNA |
spire2-202
(1)
|
Ensembl | 3,749 nt | ||
| mRNA |
spire2-203
(1)
|
Ensembl | 2,131 nt | ||
| mRNA |
spire2-204
(1)
|
Ensembl | 2,181 nt | ||
| mRNA |
spire2-205
(1)
|
Ensembl | 2,722 nt |
Interactions and Pathways
No data available
Plasmids
No data available