Gene
asah2
- ID
- ZDB-GENE-041112-1
- Name
- N-acylsphingosine amidohydrolase 2
- Symbol
- asah2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Exhibits N-acylsphingosine amidohydrolase activity. Involved in ceramide metabolic process. Localizes to Golgi membrane; apical plasma membrane; and endoplasmic reticulum membrane. Orthologous to several human genes including ASAH2B (N-acylsphingosine amidohydrolase 2B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR031329 | Neutral/alkaline non-lysosomal ceramidase, N-terminal |
| Domain | IPR031331 | Neutral/alkaline non-lysosomal ceramidase, C-terminal |
| Family | IPR006823 | Neutral/alkaline nonlysosomal ceramidase |
| Homologous_superfamily | IPR038445 | Neutral ceramidase, C-terminal domain superfamily |
Domain Details Per Protein
| Protein | Length | Neutral/alkaline nonlysosomal ceramidase | Neutral/alkaline non-lysosomal ceramidase, C-terminal | Neutral/alkaline non-lysosomal ceramidase, N-terminal | Neutral ceramidase, C-terminal domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:Q5W7F1
|
743 |
Interactions and Pathways
No data available
Plasmids
No data available