Gene
elac2
- ID
- ZDB-GENE-041111-227
- Name
- elaC ribonuclease Z 2
- Symbol
- elac2 Nomenclature History
- Previous Names
-
- im:7145112
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable 3'-tRNA processing endoribonuclease activity. Predicted to be involved in mitochondrial tRNA 3'-trailer cleavage, endonucleolytic. Predicted to act upstream of or within tRNA processing. Predicted to be located in mitochondrial nucleoid. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 17. Orthologous to human ELAC2 (elaC ribonuclease Z 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7145112 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| combined oxidative phosphorylation deficiency 17 | Alliance | Combined oxidative phosphorylation deficiency 17 | 615440 |
| {Prostate cancer, hereditary, 2, susceptibility to} | 614731 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Metallo-beta-lactamase | Ribonuclease Z/Hydroxyacylglutathione hydrolase-like | tRNase Z endonuclease | Zinc phosphodiesterase ELAC protein 2-like |
|---|---|---|---|---|---|
|
UniProtKB:F1QHE2
|
819 |
Interactions and Pathways
No data available
Plasmids
No data available