Gene
cenpf
- ID
- ZDB-GENE-041111-205
- Name
- centromere protein F
- Symbol
- cenpf Nomenclature History
- Previous Names
-
- im:7140452
- im:7144238
- im:7154719 (1)
- im:7156761
- si:ch211-152h14.2
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable dynein complex binding activity. Involved in heart looping; kidney development; and ventricular system development. Acts upstream of or within cilium assembly. Predicted to be active in chromosome, centromeric region; nucleus; and spindle pole. Is expressed in proliferative region. Human ortholog(s) of this gene implicated in Stromme syndrome. Orthologous to human CENPF (centromere protein F).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 16 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7144238 (1 image)
- IMAGE:7140452 (10 images)
- IMAGE:7156761 (1 image)
- IMAGE:7154719 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Waters et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Stromme syndrome | Alliance | Stromme syndrome | 243605 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Centromere protein Cenp-F | Centromere protein Cenp-F, leucine-rich repeat-containing domain | Centromere protein Cenp-F, N-terminal | Kinetochore protein Cenp-F/LEK1, Rb protein-binding domain |
|---|---|---|---|---|---|
|
UniProtKB:F1Q7X5
|
2708 | ||||
|
UniProtKB:A0A286Y8J7
|
2675 |
Interactions and Pathways
No data available
Plasmids
No data available