Gene

brwd1

ID

ZDB-GENE-041111-120

Name

bromodomain and WD repeat domain containing 1

Symbol

brwd1 Nomenclature History

Previous Names

im:7140700

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Description

Predicted to have insulin receptor binding activity. Predicted to be involved in cytoskeleton organization; regulation of cell shape; and regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Orthologous to human BRWD1 (bromodomain and WD repeat domain containing 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7140700 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With brwd1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Ciliary dyskinesia, primary, 51	620438

Associated With brwd1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018359	Bromodomain, conserved site
Conserved_site	IPR019775	WD40 repeat, conserved site
Domain	IPR001487	Bromodomain
Family	IPR052060	Bromodomain and WD repeat-containing
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036322	WD40-repeat-containing domain superfamily
Homologous_superfamily	IPR036427	Bromodomain-like superfamily
Repeat	IPR001680	WD40 repeat
Repeat	IPR020472	G-protein beta WD-40 repeat